We all know that brain and head injuries can cause drastic personality change in people. The most of which being Phineas Gage.
In a more recent case, a 37 yr old woman had been admitted to an epilepsy clinic in Germany. She had no previous mental health problems . She had reported feelings of fear, nausea as well as delusions she was a man. She reportedly felt her voice becoming deeper like a man and that she saw her own arms as male with male hair growth.
She saw the same thing among other woman; that they appeared to change into men before her eyes. An MRI scan showed a tumor linked to her seizures, located in the amygdala, of which is linked to one's sense of identity "including aspects like familiarity, emotional state, and sex, and past studies revealed that electrical stimulation of the temporal lobe triggered doubt about sexual identity." Anticonvulsive drugs prevented furture delusions and seizures.
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